CLENBUTEROL

CLENBUTEROL, brand of Clenbuterol Hydrochloride tablets, is a direct-acting sympathomimetic with mainly beta-adrenergic activity and a selective action on beta2 receptor (a beta2 agonist). Each tablet contains 40 microgram of Clenbuterol Hydrochloride, Ph.Eur.5.5, micronized grade. It is designated chemically as 1-(4-Amino-3,5- dichloropheny1)-2-tert-butylaminoethanol hydrochloride.It occurs as white or almost white crystalline powder. Soluble in water and in alcohol; slightly soluble in   acetone. 5% solution in water has a pH of 5.0 to 7.0.

CLENBUTEROL acts through selective stimulation of the ß32 - receptors. It differs from other ß2-specific sympathomimetic by the low effective dose, long biological half-life, rapid and complete absorption by oral administration. It has properties similar to those of salbutamol. It is used as a bronchodilator in the management of reversible airways obstruction, as in asthma and certain patients with chronic obstructive pulmonary disease.